HAPTEN CHEMISTRY AND ANTIBODY GENERATION

We design the
small molecules
that antibodies
learn to bind

Rational hapten design and high-affinity antibodies, engineered into immunoanalytical platforms (ELISA, lateral-flow, and biosensors) for sensitive and specific detection.

30

+
YEARS OF EXPERTISE

250

+
PUBLICATIONS

30

+
PATENTS GRANTED

40

+
COLLECTION MOLECULES
ABOUT US

From a molecule on paper
to a tool in the field.

01 · Group

Who we are

A multidisciplinary group of organic chemists, biochemists and analytical scientists at IATA-CSIC and the University of València, with 30+ years in hapten chemistry and immunoanalysis.

02 · Research

Our research

Rational design of haptens and production of highly specific antibodies — spanning molecular modelling, synthesis, antibody development and applied immunoassay engineering.

03 · Resources

Resources

Three specialised laboratories spanning organic synthesis, analytical immunotechnology and cell culture — equipped for hapten design, antibody production and immunoassay development.

https://www.youtube.com/watch?v=8Qyc3Rcw43Y
OUR WORK

Advancing research and training in antibodies and immunochemical detection.

Research

Our projects focused on developing innovative antibodies and immunoanalytical tools to detect chemical contaminants.

Training

Explore the group’s doctoral theses on hapten synthesis, antibodies and immunochemical detection methods.

TECHNOLOGY TRANSFER

Interested in licensing our antibodies or co-developing an assay?

We collaborate with industry, start-ups and research institutions worldwide, building on a long-standing network of scientific collaborations with research groups in different countries. Our collection and immunoassay platforms are available for licensing, joint evaluation in specific applications and custom development.

SELECTED PUBLICATIONS

Recent work

  • From Leuco to Blue: Photochemical Redox Amplification for Small-Molecule Immunodetection
    Moya-Cavas, Tamara, Benito-Peña, Elena, Sargsyan, Arev et al. · Journal of the American Chemical Society · 2026 · DOI 10.1021/jacs.6c06373
  • Validation of novel immunoassays according to European legislation for the rapid analysis of ochratoxin A in cereal, grape, and dried vine fruit samples
    Cantero-Gómez, M., López-Puertollano, D., Navarro-Fuertes, I. et al. · Journal of Food Composition and Analysis · 2026 · DOI 10.1016/j.jfca.2025.108569
  • Click chemistry-based bioconjugates for direct immunochemical analysis of the mycotoxin citrinin
    Ulloa-Campos, Diego, López-Puertollano, Daniel, Abad-Somovilla, Antonio et al. · Analytica Chimica Acta · 2026 · DOI 10.1016/j.aca.2026.345314
  • Fast-tracking rapid cyanotoxin detection: A novel immunoassay for emerging dihydroanatoxins
    Suay-Fuentes, Daniel, Navarro-Fuertes, Ismael, Abad-Fuentes, Antonio et al. · Chemosphere · 2025 · DOI 10.1016/j.chemosphere.2025.144503
  • Competitive cytometry-based immunoassay for patulin determination in apple juice
    López-Puertollano, Daniel, Duncan, Hadyn, Abad-Somovilla, Antonio et al. · Microchemical Journal · 2025 · DOI 10.1016/j.microc.2025.113287
FROM THE LAB

Latest news

40th International Conference on Environmental & Food MonitoringMeetings

40th International Conference on Environmental & Food Monitoring

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30th EFFoST International Conference. Targeted Technologies for Sustainable Food Systems

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11th International Conference on Toxic CyanobacteriaMeetings

11th International Conference on Toxic Cyanobacteria

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A research group specialising in hapten chemistry, antibody production and immunoanalytical tools for food safety, environmental and clinical applications.